Roma fell to a surprise 1-0 defeat in Turkey

Yusuf Simsek’s first-half strike for the Turks was enough to see off their more illustrious opponents.

Roma, who lie second in Serie A, went into the tie without Francesco Totti, Antonio Cassano and Vincenzo Montello.

Gaziantepspor fans had set fire to stadium seats just four days earlier after their side lost to Fenerbahce.

Genclerbirligi also upset Italian opponents, winning 1-0 at Parma to make it a memorable night for Turkish sides.

Ali Tandogan hit the post early on for the visitors as both sides toiled in heavy snow, but Josip Skoko claimed the winner on the hour.

Their compatriots Galatasaray came from two goals down to keep their hopes alive with a 2-2 draw at home to Spanish side Villarreal.

Sonny Anderson and Juan Riquelme gave Villarreal a two-goal advantage after 22 minutes but Galatasaray replied through Murat Erdogan and Cesar Prates.

Ronaldinho scored the only goal in Barcelona’s 1-0 win away to Brondby, reacting smartly after his own free-kick had cannoned off the crossbar.

Valencia needed an injury-time winner by David Navarro to beat Besiktas 3-2 after strikes by Mohamed Sissoko and Fabian Canobbio saw them twice cancel out Daniel Pancu goals for the Turkish champions.

Inter Milan also led twice at Sochaux, through Christian Vieri and Alvaro Recoba, but Pierre-Alain Frau’s brace saw the French side earn a 2-2 draw.

Real Mallorca posted a 3-0 victory away to Spartak Moscow, courtesy of strikes by Samuel Eto’o, Toni Gonzalez and Jesus Perera.

Marseille will take a slender advantage into the second leg of their clash with Ukrainian outfit Dnipro after Didier Drogba gave them a 1-0 home victory, while Marouane Chamakh netted as Bordeaux won by the same margin at Groclin, Polish conquerors of Manchester City.

In Belgium, Club Brugge triumphed 1-0 against Hungarian outfit Debrecen, courtesy of a Rune Lange goal, while Zlatko Zahovic was on target as Benfica recorded a 1-0 victory over Rosenborg.

Perugia held PSV Eindhoven to a 0-0 draw, while Auxerre and Panathinaikos shared the same scoreline.